An extremely serious allergic reaction to this drug is exceptional. Nevertheless, get clinical assist without delay for those who recognize any signs or symptoms of a serious allergic response, which includes:

monoamine oxidase inhibitors (MAOIs) for example moclobemide and phenelzine used in the treatment of despair

Opioids may cause habit and you may get withdrawal signs and symptoms for those who stop taking it all of a sudden. Your prescriber ought to have explained how long you may be taking it for and when it is suitable to halt, how To achieve this properly.

長期使用時，身體可對可待因產生耐藥性，令藥效減弱，並有可能產生依賴性。

Hyperalgesia Hyperalgesia could be diagnosed In case the affected person on very long-time period opioid therapy offers with elevated ache.

Posology Older people A person to 2 tablets each individual 4 to six hrs when essential to a maximum of 8 tablets for every 24 hours.

Quickly halting this medication may possibly bring about withdrawal, particularly if you have applied it for many years or in substantial doses. To stop withdrawal, your health practitioner might lower your dose slowly but surely.

CYP2D6 metabolism Codeine is metabolised by the liver enzyme CYP2D6 into morphine, its Lively metabolite. If get more info a individual features a deficiency or is totally missing this enzyme an sufficient analgesic impact won't be received. Estimates indicate that approximately seven% of the Caucasian population could have this deficiency.

A generic drug is actually a medicine which is click here made to generally be similar to a medication which includes by now been authorised, and which is frequently branded.

Missed dose If you're taking this medication on an everyday plan and you also overlook a dose, get it as soon as you keep in mind. Whether it is near the time of the next dose, skip the missed dose. Just take your up coming dose in the typical time. Will not double the dose to capture up.

For anyone who is employing a liquid type of the medication, utilize a medication measuring gadget to cautiously evaluate the prescribed dose. Do not use a house spoon because you might not get the right dose. For anyone who is taking the suspension, shake the bottle effectively before Every single dose.

The leaflet will point out from the “ pregnancy and breast-feeding” subsection with the area two “ Right before taking your drugs” : Co-codamol is contraindicated in breast-feeding

2. Qualitative and quantitative composition Each effervescent pill incorporates 500mg paracetamol and 30mg codeine phosphate hemihydrate.

four.6 Fertility, pregnancy and lactation Thorough consideration need to be supplied ahead of prescribing the product for Expecting patients. Typical use for the duration of pregnancy may possibly trigger dependence from the foetus, bringing about withdrawal signs or symptoms inside the neonate.